Before Your Visit 2001 Jun; 138(6):939-41. . View in PubMed, Induction of Immune Response after Allogeneic Wilms' Tumor 1 Dendritic Cell Vaccination and Donor Lymphocyte Infusion in Patients with Hematologic Malignancies and Post-Transplantation Relapse Biol Blood Marrow Transplant. Alexis’ blood was collected and sent to the lab so that his T-cells could be genetically engineered to recognize and destroy leukemia cells. 2010 Mar 15; 16(6):1894-903. . View in PubMed, Improving access to novel agents for childhood leukemia Cancer. View in PubMed, Immunotherapy for pediatric leukemia Front Oncol. View in PubMed, Long-term remission in a child with refractory EBV(+) hydroa vacciniforme-like T-cell lymphoma through sequential matched EBV(+)-related allogeneic hematopoietic SCT followed by donor-derived EBV-specific cytotoxic T-lymphocyte immunotherapy Bone Marrow Transplant. He has been in practice for more than 20 years. 2018 05 21; 10(5). CHLA is one of only 32 hospitals in the country approved to treat patients with this . View in PubMed, 5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox Proc Natl Acad Sci U S A. T.J. Martell Foundation has raised more than $280 million for cancer research. 2020 02; 21(2):e104-e116. The Team: $156,565 TOTAL RAISED SO FAR David Abbott. 2011 Jun 02; 117(22):5835-49. . 2017 Sep 10; 9(9). View in PubMed, Reduced-intensity allogeneic stem cell transplantation in children and young adults with ultrahigh-risk pediatric sarcomas Biol Blood Marrow Transplant. 2016 12; 22(12):2149-2154. . View in PubMed, Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study Clin Cancer Res. 2013 Nov; 15(11):1406-15. . 2014 Oct; 49(10):1259-65. . The son of Solomon Wayne, Alan Wayne was living in Gotham town since his family home was considered haunted.However, sometime in the second half of the 19th century, he was walking on a bridge when … 2004 Sep 15; 22(18):3798-804. . View in PubMed, Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells J Extracell Vesicles. “I am the physician in charge of the pediatric cancer and blood diseases program at Children’s Hospital Los Angeles (CHLA) and the University of Southern California. 2014 Jan; 20(1):4-13. . 2011 Jun; 52 Suppl 2:79-81. . Dr. Alan S Wayne is a Hematology / Oncology Specialist in Los Angeles, California. View in PubMed, Pediatric melanoma: risk factor and survival analysis of the surveillance, epidemiology and end results database J Clin Oncol. Team overview for Leukemia and Lymphoma Program. View in PubMed, Results from an international phase 2 study of the anti-CD22 immunotoxin moxetumomab pasudotox in relapsed or refractory childhood B-lineage acute lymphoblastic leukemia Pediatr Blood Cancer. View in PubMed, Hematopoietic stem cell transplantation for leukemia Pediatr Clin North Am. 2009 Dec; 41(3):209-16. . 2013 Nov; 19(11):1537-45. . Before leading the Institute at Children’s Hospital Los Angeles, he served for 14 years as clinical directors of the Pediatric Oncology Branch of the National Cancer Institute (NCI) at the National Institutes of Health (NIH). 2014 Jul; 20(7):1033-9. . Biol Blood Marrow Transplant. View in PubMed, Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737 Leuk Lymphoma. . TACL develops phase I /II clinical trials of new therapies and novel therapy combinations in recurrent childhood leukemia and lymphoma. View in PubMed, Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial Clin Cancer Res. View in PubMed, Ancillary therapy and supportive care of chronic graft-versus-host disease: national institutes of health consensus development project on criteria for clinical trials in chronic Graft-versus-host disease: VAncillary Therapy and Supportive Care Working Group Report. 2010 Nov; 95(11):1873-9. . So when Alexis Bonilla was 11 years old and his disease returned for the third time, his doctor immediately referred him to CHLA. Programs and Services View in PubMed, Desferrioxamine provocative test: methodology for estimating iron and total iron binding capacity Blood. Alan S Wayne Relapse of cancer remains one of the primary causes of treatment failure and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). 2016 Feb; 34(1):61-5. . Blood. View in PubMed, A validated pediatric disease risk index for allogeneic hematopoietic cell transplantation Blood. History. However, of those who relapse, only a minority survive long-term. Alan Wayne, MD, and Michael Pulsipher, MD, helped . View in PubMed, Children as hematopoietic cell donors in research: when is it approvable? View in PubMed, Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States Blood. 2020 05; 67(5):e28112. Dr. Alan Wayne, CHLA, and Helen Wayne attend The T.J. Martell Foundation 43rd New York Honors Gala at Cipriani 42nd Street on October 15, 2018 in New York City. Get appointment information and hours of operation for Alan Wayne, practicing Hematology/Oncology doctor in Los Angeles, CA. Alan S. Wayne, M.D. . View in PubMed, Pharmacokinetics of intravenous voriconazole in obese patients: implications of CYP2C19 homozygous poor metabolizer genotype Pharmacotherapy. View in PubMed, Perioperative management for cholecystectomy in sickle cell disease J Pediatr Surg. 2012 Nov 01; 120(18):3635-46. . 2015 Mar; 168(6):865-73. . View in PubMed, Feasibility of treating post-transplantation minimal residual disease in children with acute leukemia Biol Blood Marrow Transplant. 2012 May; 18(5):698-707. . 2018 02 20; 115(8):E1867-E1875. This is a past event. 2010 Oct; 16(10):1325-46. . Alan S. Wayne, MD, is the Director of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles and serves as head of the Division of Hematology, Oncology and Blood and Marrow Transplantation in the Department of Pediatrics. 2015 Jun; 62(6):964-9. . 2002; 4(6):539-49. . 2016 05; 15(5):1053-62. . View in PubMed, Restricted cell surface expression of receptor tyrosine kinase ROR1 in pediatric B-lineage acute lymphoblastic leukemia suggests targetability with therapeutic monoclonal antibodies PLoS One. 2013 Nov; 37(11):1551-6. . Existing Patients or Family Members: 323-361-4624, New Patients, Referrals and 2nd Opinions: 323-361-4100, About Our Hospital View in PubMed, Allogeneic hematopoietic stem cell transplantation for myeloproliferative disorders and myelodysplastic syndromes Hematol Oncol Clin North Am. 2012 Jul 12; 120(2):244-6. . View in PubMed, Myeloid lineage switch following chimeric antigen receptor T-cell therapy in a patient with TCF3-ZNF384 fusion-positive B-lymphoblastic leukemia Pediatr Blood Cancer. View in PubMed, Barriers to bone marrow transplantation for sickle cell anemia Biol Blood Marrow Transplant. View in PubMed, Characterization of CD22 expression in acute lymphoblastic leukemia Pediatr Blood Cancer. View in PubMed, Biological roles and potential applications of immune cell-derived extracellular vesicles J Extracell Vesicles. Alan S. Wayne, M.D. View in PubMed, Introduction to the reports from the National Cancer Institute First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation Biol Blood Marrow Transplant. View in PubMed, NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on disease-specific methods and strategies for monitoring relapse following allogeneic stem cell transplantationpart II: chronic leukemias, myeloproliferative neoplasms, and lymphoid malignancies. Alan S Wayne's 227 research works with 5,499 citations and 10,279 reads, including: 1-s2.0-S1470204519307296-mmc1.pdf advancement. View in PubMed, CAR T-cell product performance in haematological malignancies before and after marketing authorisation Lancet Oncol. 2015 Feb 07; 385(9967):517-528. . Alan S. Wayne, MD Director, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles Head, Division of Hematology, Oncology and Blood and Marrow Transplantation at the Keck School of Medicine of the University of Southern California (USC) Choose either the "Merged" or "Side-by-Side" comparison format to specify how the two study versions are to be displayed. 2015 Jan 29; 125(5):784-92. . CHLA - wrote - Team CHLA is fundraising for our pediatric cancer research program as part of the Nautica Malibu Triathlon. . Dear friends and family, After couple of years of participating in the biking portion of the Nautica Malibu Triathlon, I decided to run the classic distance course this year (1/2 mile swim, 17 miles bike, 4 mile run; which is making Mushi very nervous ☺). View in PubMed, Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation Blood. 2018 Feb; 65(2). 2017; 6(1):1294368. . 2020 Jul 09; 136(2):210-223. . 1996 May; 2(2):100-4. . View in PubMed, Cytotoxicity of the anti-CD22 immunotoxin HA22 (CAT-8015) against paediatric acute lymphoblastic leukaemia Br J Haematol. View in PubMed, Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia Blood. View in PubMed, Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group Pediatr Hematol Oncol. Dr. Alan Wayne, MD is a Pediatric Hematology-Oncology Specialist in Los Angeles, CA and has over 36 years of experience in the medical field. View in PubMed, Sibling stem cell donor experiences at a single institution Psychooncology. Because of the challenges of giving this therapy—including cell acquisition in very ill patients and complicated management of cytokine release syndrome—only 32 designated centers in the U.S. will be initially approved to administer Kymriah. Weili Sun, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, USC‐Norris Comprehensive Cancer Center, University of Southern California, 4650 Sunset Boulevard, MS#54, Los Angeles, CA 90027. CHLA is the only center in Southern California approved to offer CAR-T therapy to these patients. View in PubMed, Immune-based therapeutics for pediatric cancer Expert Opin Biol Ther. 2012 Sep; 87(9):916-22. . View in PubMed, Is another antibody conjugate against ALL needed? View in PubMed, Hematopoietic stem cell donation in children: a review of the sibling donor experience J Psychosoc Oncol. … 2008 Sep 17; 100(18):1271-3. . 2013 Apr 26; 288(17):12305-12. . . View in PubMed, NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on Disease-Specific Methods and Strategies for Monitoring Relapse following Allogeneic Stem Cell TransplantationPart I: Methods, acute leukemias, and myelodysplastic syndromes.

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